Long-TermPotentiation相关论文
Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyrami
Radiation therapy is a standard treatment for head and neck tumors. However, patients often exhibit cognitive impairment......
Synaptic associativity,a feature of Hebbian plasticity wherein coactivation of two inputs onto the same neuron produces ......
Involvement of microglia and interleukin-18 in the induction of long-term potentiation of spinal noc
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Hydroxysafflor yellow A improves learning and memory in a rat model of vascular dementia by increasi
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Objective Alzheimers disease(AD)is a progressive and degenerative disorder accompanied by cognitive impairment,but effec......
Objective Long-term potentiation(LTP)of synaptic transmission is thought to be a direct reflection of synaptic informati......
Aim: FSC231 is the specifical PDZ domain inhibitor of PICK1 which has been suggested as a potential drug target against ......
Acoustically evoked potentials in the lateral nucleus of the amygdala is enhanced by tetanic stimula
The lateral nucleus of the amygdala (LA) receives axonal projections from the auditory thalamus and mediates auditory fe......
A Novel Unimolecular GLP-1/GIP/Gcg Triagonist Improves Cognitive Function and Hippocampal Synaptic P
Type 2 diabetes mellitus (T2DM) is a risk factor for Alzheimers disease (AD). Glucagon-like peptide-1 (GLP-1) and glucos......
[Glyl4]-Humanin reverses depressive actions of amyloid β-protein fragment 25-35 on long-term potenti
Alzheimers disease (AD) is the most prevalent neurodegenerative disease in aged people leading to progres-sive loss of m......
Neonatal Ketamine Exposure Causes Impairment of Long-term Synaptic Plasticity in the Anterior Cingul
Ketamine,a dissociative anesthetic most commonly used in many pediatric procedures,has been reported to cause widespread......
α1-adrenoceptors in the hippocampal dentate gyrus involve in learning-dependent long-term potentiati
The hippocampus is the key structure for learning and memory in mammals,and long-term potentiation(LTP)is an important c......
Possible synaptic mechanisms underlying LTP of intraspinal neuronal network activation in spinal cor
Our previous studies have shown that not only long-term potentiation(LTP)of afferent(dorsal root)and descending(ventrola......
Effect of NR2B antagonist against Aβ25-35 induced acute synaptic plasticity disruption in rat hippoc
Aim: Amyloid beta (Aβ)-induced synaptic dysfunction is thought to be an important event in early stage of Alzheimers di......
Rattin protects against Aβ25-35 indued impairments in synaptic plasticity and spatial cognition of r
Rattin (RN), a humanin-like peptide, shared with Humanin ability to protect neurons against amyloid β protein (Aβ)-ind......
Melamine induced synaptic plasticity impairment associated with change of information flown in Wista
The rhythms of local field potentials (LFPs) are reported to be related to cognition whose underling mechanism is synapt......
Extensive research has shown that the aggregation and toxicity of amyloid -beta protein (A β) are closely related to th......
Long-term potentiation(LTP)is the key cellular mechanism for physiological learning and pathological chronic pain.Postsy......
Behavioral and electrophysiological study on the neuroprotective effects of lixisenatide against Aβ2
Although glucagon-like peptide-1 (GLP-1), an insulin-releasing gut hormone, has been thought as a promising treatment fo......
Amyloid β protein(Aβ)is the main component of extracellular senile plaques in the brain of patients with Alzheimers di......
The Repair Effects of Fullerenol on the Damage of Hippocampal Functions Caused by Lead Exposure in R
As a kind of functional water-soluble fullerene derivative,fullerenol has driven extensive applications in biomedical fi......
Patients with damage to the medial temporal lobe show deficits in forming new declarative memories but can still recall ......
The exact roles of acid-sensing ion channels(ASICs)in synaptic plasticity remain elusive.Here,we address the contributio......
Long-term depression(LTD)and long-term potentiation(LTP)at cerebellar parallel fiber-Purkinje cell(PF-PC)synapses play c......
LTP of EPSP evoked by ipsilateral pericentral canal stimulation in neonatal rat spinal cord motoneur
Objective To explore the possible synaptic plasticity of excitatory synaptic transmission from ipsilateral pericentral c......
Roles of acid-sensing ion channel 1a in synaptic plasticity in the hippocampus:Revisited by multi-el
Acid-sensing ion channels(ASICs)are proton-gated cation channels involved in a variety of physiological and pathological......
Induction of spinal GluN2B-dependent LTP via BDNF contributes to the development of neuropathic pain
In previous studies,we have found that the GluN2B-containing NMDA(NMDA-GluN2B)receptors-mediated long-term potentiation(......
AIM Previous pharmacological studies demonstrated that LW could ameliorate the decline of the learning and memory in sen......
Impairment of dopaminergic facilitation of synaptic potentiation in the anterior cingulate cortex in
Prefrontal cortex,including the anterior cingulate cortex (ACC),has been documented to play key roles in learning,memory......
Soluble amyloid β-enhanced LTD in rat dentate gyrus of hippocampus is mGluR1/5-dependent and involve
Accumulation of amyloid beta (Aβ) protein is a key pathogenic element of Alzheimers disease.It is reported that the Aβ......
Spinal Long-term Potentiation Underlies Chronic Pain via CSF1 Signaling-dependent Microglial Activat
Spinal long-term potentiation(LTP)at C-fiber synapses induced by injury or electrical high frequency stimulation(HFS)of ......
Liuwei Dihuang decoction(LW),a classic formula in traditional Chinese medicine(TCM),has been used for nearly one thousan......
Sub-chronically exposure benzo[a]pyrene inhibiting the Long-Term Potentiation in rat hippocampal CAI
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Objective It is well documented that ethanol exposure alters GABA (γ-aminobutyric acid)-releasing synapses, and ethanol......
Soluble amyloid β-enhanced LTD in rat dentate gyrus of hippocampus is mGluR1/5-dependent and involve
Accumulation of amyloid beta (Aβ) protein is a key pathogenic element of Alzheimers disease.It is reported that the Aβ......
Sexual contact decreases contextual fear and prevents impairment of hippocampal long-term potentiati
Hippocampal long-term potentiation (LTP) is believed to be the mechanism underlying certain types of memory,which is exq......
Effects of Microwave Exposure on Cognitive Function, Long-term Potentiation and Hippocampal Structur
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Disruption of the CaMKIICREB Signaling Is Associated with Zinc Deficiency-induced Learning and Memor
As an important region of brain,hippocampus is affected by levels of zinc ions.Many studies have shown that zinc deficie......
Modulation of long-term potentiation in the hippocampus by pharmacological approach： A novel strateg
学习并且存储器不仅提供认知的基础，但是也是仔细与有关感觉并且马达功能。象 Alzheimer 鈥檚 疾病和 Parkinson 鈥檚 疾病那样的 N......
The content of total flavonoids in an extract of Ginkgo biloba, called GBE50, is 44% by weight. This is significantly gr......
Status epilepticus has been shown to activate the proliferation of neural stem cells in the hippocampus of the brain, wh......
Study on Long-term Potentiation in Developing Rat Visual Cortex during the Critical Period of Plasti
Purpose: To study the property of LTP in layers Ⅱ～Ⅳof the rats visual cortex at different postnatal days induced by pai......
目的观察白藜芦醇（Res）对记忆减退大鼠被动回避能力及对cAMP反应元件结合蛋白（CREB）表达的影响。方法按体质量将雌性Wistar大鼠随机分......
Tweety-Homolog 1 Facilitates Pain via Enhancement of Nociceptor Excitability and Spinal Synaptic Tra
Tweety-homolog 1 (Ttyh1) is expressed in neural tissue and has been implicated in the generation of several brain diseas......
目的 研究出生前后不同浓度慢性铝暴露对年轻大鼠海马长时程增强的影响,进一步探讨铝损害学习与记忆的突触机制.方法 对照组、低浓......
Electric stimulation at sciatic nerve evokes long-term potentiation of cornu dorsale medullae spinal
BACKGROUND: Long-term potentiation of cornu dorsale medullae spinalis field potential in adult rats has already been rep......
目的 研究纹状体边缘区与脑内其他与学习记忆有关脑区间的关系。方法 高频刺激穿通纤维-齿状回通路的海马诱发长时程增强（LTP），观察海......
